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With an ageing baby boomer generation, and few concrete, scientific advancements towards a prescribed drug or treatment in the last 10 years, Dementia and Alzheimer’s have become increasingly concerning conditions in the UK. As a result, the urgency to find a treatment is also becoming a pressing concern, as researchers endeavour to find a way of preventing the progression of these diseases.

With the increase in awareness, it has been incredibly encouraging to witness a greater commitment from governments, organisations and charities towards funding Alzheimer’s research in the hope of finding a cure; a commitment we can only hope will pay off in the near future. 

What is Alzheimer’s Disease and Dementia?


Alzheimer’s Disease and Dementia are both currently incurable conditions which affect a person's brain, causing symptoms such as a decline of memory, as well as struggling with speaking or orientation, which can impede on sufferer’s quality of life and often require specialist care. As a result, they are diseases that can put a lot of strain on the families of sufferers, as well as the individuals themselves.

Currently, there are more than 850,000 people in Britain suffering with Dementia, and over the next 30 years the number of people to be diagnosed with Alzheimer’s disease is expected to go into the tens of millions, as the population continues to age. Although therapists and scientists have been making progress on issues such as how to best live with dementia, the need to find an effective cure still remains. 

The New Alzheimer’s and Dementia Breakthrough


Earlier this year, there was a possible breakthrough towards discovering a treatment for Dementia. Researchers at the University of Cambridge, while researching a new type of Cancer drug, found a possible way to reduce the risk of people developing Alzheimer’s and Dementia.

The symptoms of Alzheimer’s begin when clumps of deformed protein, known as amyloid, build-up in the brain. 

These researchers found while testing a drug called Bexarotene, currently used to treat Lymphoma, that it could potentially stop these build ups of protein, thus preventing Alzheimer’s in later life. 

This therapy is called ‘neurostatin’, and lead researcher Prof Michele Vendruscolo believes people will be taking ‘neurostatin’ as early as their 30’s, to help prevent a build-up of amyloid and consequently stop the progress of the disease in the human brain.

Although it is still too soon to say whether this is the concrete breakthrough in Alzheimer’s research that has been awaited for the last decade, this discovery is extremely positive and can undoubtedly lead to preventing the number of potential Dementia cases in the future. 

As leading providers of Alzheimer’s and Dementia care services, we understand how these diseases can be great strains on sufferers and their loved ones. We also understand the need for people who are battling Alzheimer’s or Dementia to remain as independent as possible, and their wish to be able to continue living in their own home, which is why we provide a range of tailored home care services to ensure the highest quality of life to all of our clients.

If you’re interested in our Alzheimer’s and Dementia care services, please feel free to download our brochure, or get in touch with either our Birmingham, Bradford or Leicester offices for more information. 
alzheimer's disease

The fight against Alzheimer’s disease and Dementia is an ongoing battle, but this year we've seen some major breakthroughs in research as we come closer to a cure. 

Since the first case was diagnosed over a century ago by Dr. Alois, Alzheimer, our understanding of this disease has evolved greatly. It was not so long ago that people assumed Alzheimer’s and Dementia could simply occur in old age; it’s only in recent times that we have learnt that this is not the case. With predictions that over 150 million people worldwide will suffer from Alzheimer’s in the next 20 years, 2015 has been a big year with significant triumphs and advancements in the fight against Alzheimer’s. 

Alzheimer’s Blood Test Could Give Early Diagnosis 


British researchers have developed a test to diagnose Alzheimer’s disease in its earliest stages, before any physical symptoms are visible. 

This is recognized through ‘markers’ in a patient’s blood, which are different from those seen in healthy people. This research was conducted at the University of Nottingham, and researchers are now developing a quick and easy test to be performed in clinics. 

This early diagnosis can give potential sufferers a chance to change aspects of their diet and lifestyle, as well as starting treatment earlier in order to stem the disease. 

Miniature Brain-in-a-Dish can Help Advance Alzheimer’s Research 


Rene Anand, Professor of Biological Chemistry and Pharmacology at Ohio State University, and a research team have developed an organoid that looks like a miniature human brain. 

This miniature human brain has been grown ethically through the use of human skin cells, and coaxed into developing to resemble that of a 5 month old fetus. Not only could this open up new avenues of testing in the pursuit towards finding a cure, but it could also remove the need to use rats and mice in order to conduct research, a practice which is considered by most to be outdated and unethical.

Virtual Reality Maze ‘Predicts Alzheimer’s Disease’ 


A study suggests that Alzheimer’s disease can be detected years before any physical symptoms are made apparent, through the use of a virtual reality test. People aged 18 to 30, an age group that is unlikely to be worried about Alzheimer’s disease, were are asked to navigate through a virtual maze in order to test the function of certain brain cells. 

This study, led by Lukas Kunz of the German Centre for Neurodegenerative Disease in Bonn, showed results which could "provide a new basic framework for preclinical research on Alzheimer’s disease", and "provide a neurocognitive explanation of spatial disorientation in Alzheimer’s disease.” While it is far from certain that the young people in this study will go on to develop Alzheimer’s, characterising early brain changes associated with genetic risk factors is vital, in helping researchers better understand why some people are more likely be at risk of developing the disease in later life. 

Government Pledges £300m on Dementia Research 


Earlier this year, the government pledged more that 300 million pounds worth of research into dementia, as well as providing additional training for NHS workers on how to care for people suffering with Dementia. 

Prime Minister, David Cameron has described the disease as “one of the greatest challenges of our lifetime”. As well as pledging funds to research and Alzheimer’s care, the government is also said to be setting up separate multi-million pound investment schemes, to discover new drugs and treatments in order to slow the onset of the disease, progressing towards a cure by 2025. 

This might not be a huge medical breakthrough, but considering Alzheimer’s and Dementia are one of the most underfunded research areas in medicine, this is a significant step in the right direction. 

Alzheimer’s Researchers Find Molecule That Delays Onset of Disease 


Earlier this year, a research team at the University of Cambridge found evidence to suggest that an isolated, crucial molecule secreted naturally by the human body, could delay the onset of Alzheimer’s disease. 

This study performed on mice, showed that the molecule referred to as a ‘housekeeping’ molecule, can stop the process in the brain that leads to common forms of Dementia. The substance works by slowing the build of up of protein clips in the brain, which typically appear years before symptoms such as memory loss arise. 

Although the research still has some progress to make, notably towards converting this discovery into a drug, this could potentially be the most important breakthrough since the first diagnosis. 
Samuel Cohen, who led the study, revealed these findings in an enlightening Ted Talk, stating that they have “come up with a general strategy that could work.”

While 2015 has brought with it a number of small victories in the fight against Alzheimer’s disease, we are far from finished. It is a disease which affects approximately 850,000 people living in the UK alone, and doctors are predicting that the number will grow in coming years. 

We at Sova Healthcare can see the damage and strain such diseases can cause families, which is why we strive to to provide you with the best Alzheimers home care and support services. We understand how cruel this disease can be, and that’s why our staff are highly trained and experienced in caring for your loved ones as they learn how to live with Alzheimer’s. You can download our brochure for more information, or get in touch with a member of our friendly team to discuss how we can best help you and your loved ones.